IL1R2/CD121b Protein (C-His, Human)

Product Specifications

Abbreviation

IL1R2/CD121b

Synonyms

IL1R, Interleukin-1 receptor type, IL-1R, IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, CD121 antigen-like family member B, IL-1 type II receptor, IL-1R-beta, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type I, IL-1R type II, IL-1RII

UniProt

P27930

Host

HEK 293

Tag

C-His

Applications

Cell culture

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

1. Measured by its ability to inhibit IL1β-dependent proliferation in D10.G4. 1 mouse helper T cells. The ED50 for this effect is typically 5. 5 μg/mL in the presence of 40 pg/mL of rhIL1β. 2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 500pg/mL IL1b. The EC50 for this effect is typically 20-80ng/mL.