Noggin/NOG Protein (C-hFc, Human)
Product Specifications
Abbreviation
Noggin/NOG
Synonyms
Noggin, SYM1, SYNS1
UniProt
Q13253
Host
HEK 293
Tag
C-hFc
Applications
Cell culture
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
1. Measured by its ability to inhibit BMP2-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 1. 5-2.0 μg /mL in the presence of 0.25-0.5 μg/mL of BMP-2. 2. Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3-E1 cells. The ED50 for this effect is typically 0.1-0.6 μg/mL in the presence of 50 ng/mL of hBMP4.
Function
Met 1-Cys 232
Molecular Weight
49.8 kDa
Species
Human
Curated Selection
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