ACVR2B/ActivinR-IIB Protein (C-His, Human)

ACTR-IIB, ACVR2B, Activin Receptor Type IIB, Activin Receptor Type-2B, BMP Type II Receptor, BMP Type-2 Receptor, BMPR-4, Bone Morphogenetic Protein Receptor Type II, Bone Morphogenetic Protein Receptor Type-2

1. Measured by its ability to bind biotinylated Human INHBA-his and Mouse INHBA-his in functional ELISA. 2. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.3-2 μg/mL in the presence of 10 ng/mL recombinant Activin A.