ALK-1/ACVRL1 Protein (C-His-Fc, Mouse)

Product Specifications

Abbreviation

ALK-1/ACVRL1

Synonyms

ACVRL1, ALK-1, Activin receptor-like kinase 1, SKR3, Serine/threonine-protein kinase receptor R3, TGF-B superfamily receptor type I, TSR-I, activin A receptor, activin A receptor type II-like 1

UniProt

Q61288

Host

HEK 293

Tag

C-His-Fc

Applications

Cell culture

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to inhibit BMP9-induced alkaline phosphatase production by MC3T3E1 mouse chondrogenic cells. David, L. et al. (2007) Blood 109:1953. The ED50 for this effect is typically 60-300 ng/mL in the presence of 2 ng/mL of recombiant human BMP9.