Kallikrein 11/KLK11 Protein (C-His, Human)

Product Specifications

Abbreviation

Kallikrein 11/KLK11

Synonyms

Hippostasin, KLK11, Kallikrein-11, PRSS20, Serine Protease 20, TLSP, Trypsin-Like Protease, hK11

UniProt

Q9UBX7

Host

HEK 293

Tag

C-His

Applications

Enzyme

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Measured by its ability to cleave a colorimetric peptide substrate D-Val-Leu-Lys-ThioBenzyl ester (VLK-SBzl), in the presence of 5, 5'Dithio-bis (2-nitrobenzoic acid) (DTNB) (Edwards, K. M. et al. , 1999, J. Biol. Chem. 274: 30468) . The specific activity is > 200 pmoles/min/μg. (Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)