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KWAR 23

KWAR23 is an anti-human SIRPα antibody. KWAR23 binds human SIRPα with high affinity and disrupts its binding to CD47. KWAR23 shows antitumor activity in combination with tumor-opsonizing antibodies and can be used in cancer immunotherapy research[1].

Product Specifications

CAS Number

2243227-60-1

UNSPSC

12352203

Target

CD47

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kwar-23.html

Purity

99.80

Solubility

10 mM in DMSO

Smiles

[KWAR23]

Molecular Weight

(143.4 kDa)

References & Citations

[1]Ring NG, et al. Anti-SIRPα antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc Natl Acad Sci U S A. 2017 Dec 5;114 (49) :E10578-E10585.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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