ROCK1-IN-1
ROCK1-IN-1 is a ROCK1 inhibitor with a Ki value of 540 nM. ROCK1-IN-1 can be used for the research of hypertension, glaucoma and erectile dysfunction[1].
Product Specifications
CAS Number
[692869-38-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rock1-in-1.html
Purity
98.86
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NC(C2=CC=NC=C2)=CS1)CC3=CC=C(OC)C=C3
Molecular Formula
C17H15N3O2S
Molecular Weight
325.39
Precautions
H315, H319, H320
References & Citations
[1]Green J, et al. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J Med Chem. 2015 Jun 25;58 (12) :5028-37.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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