FLT3, Human (T227M, HEK293, His)

FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Human (T227M, HEK293, His) is the recombinant human-derived FLT3 protein, expressed by HEK293 , with C-His labeled tag.

NQDLPVIKCV LINHKNNDSS VGKSSSYPMV SESPEDLGCA LRPQSSGTVY EAAAVEVDVS ASITLQVLVD APGNISCLWV FKHSSLNCQP HFDLQNRGVV SMVILKMTET QAGEYLLFIQ SEATNYTILF TVSIRNTLLY TLRRPYFRKM ENQDALVCIS ESVPEPIVEW VLCDSQGESC KEESPAVVKK EEKVLHELFG MDIRCCARNE LGRECTRLFT IDLNQTPQTT LPQLFLKVGE PLWIRCKAVH VNHGFGLTWE LENKALEEGN YFEMSTYSTN RTMIRILFAF VSSVARNDTG YYTCSSSKHP SQSALVTIVE KGFINATNSS EDYEIDQYEE FCFSVRFKAY PQIRCTWTFS RKSFPCEQKG LDNGYSISKF CNHKHQPGEY IFHAENDDAQ FTKMFTLNIR RKPQVLAEAS ASQASCFSDG YPLPSWTWKK CSDKSPNCTE EITEGVWNRK ANRKVFGQWV SSSTLNMSEA IKGFLVKCCA YNSLGTSCET ILLNSPGPFP FIQDN