13,14-Dihydro-15-keto prostaglandin D2

13, 14-Dihydro-15-keto prostaglandin D2 (DK-PGD2) is a PGD2 metabolite formed by the 15-hydroxyl PGDH pathway. 13, 14-Dihydro-15-keto prostaglandin D2 is a selective agonist for the DP2 receptor. 13, 14-Dihydro-15-keto prostaglandin D2 can inhibit ion flux in canine colonic mucosa preparation[1].

Product Specifications

CAS Number

[59894-07-4]

Product Name Alternative

DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-Dihydro-15-keto-PGD2

UNSPSC

12352211

Hazard Statement

H225, H319, H336

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/13-14-dihydro-15-keto-prostaglandin-d2.html

Concentration

28.37 mM * 500 μL in Methyl acetate

Purity

99.90

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=O)CCC(CCCCC)=O)=O

Molecular Formula

C20H32O5

Molecular Weight

352.47

Precautions

H225, H319, H336

References & Citations

[1]Larsen P, et al. Calcium-stimulated short-circuit currents in the canine proximal colonic epithelium: effects of DK-PGD2, a metabolite of prostaglandin D2. Can J Physiol Pharmacol. 2002 Nov;80 (11) :1085-94.