Ibiglustat (L-Malic acid)
Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2].
Product Specifications
CAS Number
1629063-78-0
Product Name Alternative
Venglustat (L-Malic acid) ; SAR402671 (L-Malic acid) ; GZ402671 (L-Malic acid)
UNSPSC
12352005
Hazard Statement
H302, H361, H373
Target
Glucosylceramide Synthase (GCS)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Ibiglustat_succinate.html
Purity
98.65
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O[C@@H]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CC=C(F)C=C4)=N3)C.OC(C[C@H](O)C(O)=O)=O
Molecular Formula
C24H30FN3O7S
Molecular Weight
523.57
Precautions
H302, H361, H373
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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