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Pseudouridine (Standard)

Pseudouridine (Standard) is the analytical standard of Pseudouridine. This product is intended for research and analytical applications. Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation[1][2][3][4].

Product Specifications

CAS Number

1445-07-4

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pseudouridine-standard.html

Purity

99.98

Smiles

O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CNC2=O)O[C@@H]1CO

Molecular Formula

C9H12N2O6

Molecular Weight

244.20

References & Citations

[1]Carlile TM, et al. Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells. Nature. 2014 Nov 6;515 (7525) :143-6.|[2]M Charette, et al. Pseudouridine in RNA: what, where, how, and why. IUBMB Life. 2000 May;49 (5) :341-51.|[3]Junhui Ge, et al. RNA pseudouridylation: new insights into an old modification. Trends Biochem Sci. 2013 Apr;38 (4) :210-8.|[4]Anne C Rintala-Dempsey, et al. Eukaryotic stand-alone pseudouridine synthases - RNA modifying enzymes and emerging regulators of gene expression? RNA Biol. 2017 Sep 2;14 (9) :1185-1196.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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