(d (CH2) 51, Tyr (Me) 2, Dab5, Arg8) -Vasopressin

(d (CH2) 51, Tyr (Me) 2, Dab5, Arg8) -Vasopressin (d (CH2) 5[Tyr (Me) 2, Dab5]AVP) is a specific antagonist of vasopressin V1a receptor, with a pA2 of 6.71[1].

Product Specifications

CAS Number

[176714-12-8]

Product Name Alternative

D (CH2) 5[Tyr (Me) 2, Dab5]AVP

UNSPSC

12352209

Target

Vasopressin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/d-ch2-51-tyr-me-2-dab5-arg8-vasopressin.html

Solubility

10 mM in DMSO

Smiles

O=C1CC2(CCCCC2)SSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N1)CC3=CC=C(C=C3)OC)=O)CC4=CC=CC=C4)=O)CCC(N)=O)=O)CCN)=O)C(N5[C@@H](CCC5)C(N[C@H](C(NCC(N)=O)=O)CCCNC(N)=N)=O)=O

Molecular Formula

C52H76N14O11S2

Molecular Weight

1137.38

References & Citations

[1]Chan WY, et, al. Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays. Exp Physiol. 2000 Mar;85 Spec No:7S-18S.