NS2B/NS3-IN-2
NS2B/NS3-IN-2 is a potent dengue virus (DENV) NS2B/NS3 covalent inhibitor with an IC50 of 6.0 nM and Ki of 0.66 μM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate[1].
Product Specifications
CAS Number
3010940-08-3
UNSPSC
12352005
Target
Dengue Virus; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ns2b-ns3-in-2.html
Purity
98.10
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(C(C=C1)=CC=C1OCC)(N2N=C(C=C2N)OC(C3=CC=C(C=C3)C4=CC=CC=C4)=O)=O
Molecular Formula
C24H21N3O5S
Molecular Weight
463.51
References & Citations
[1]Lin X, et al. Identification and In Silico Binding Study of a Highly Potent DENV NS2B-NS3 Covalent Inhibitor. ACS Med Chem Lett. 2022; 13 (4) :599-607.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![beta IV Tubulin (TUBB4A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3C12]](https://cdn.genprice.uk/products/937/68dd1b6a061270361ea160f4/imageurl/ta502962am.webp)
TA502962AM 100 µL
beta IV Tubulin (TUBB4A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3C12]
Sign In for Pricing
View Details 
TRC-N519937-100MG 100 mg
4-(6-Nitro-3-pyridinyl)-piperazine-2,2,6,6-d4
Sign In for Pricing
View Details 
BNUB2988-500 1x 500 µL
BCL10 (MALT-Lymphoma Marker) (BL10/2988R), 0.2mg/mL
Sign In for Pricing
View Details