KSCM-1
KSCM-1 is a selective sigma-1 receptor ligand with a Ki of 27.5 nM. KSCM-1 shows more selective for sigma-1 over sigma-2, and shows no significant affinity at non-sigma receptors[1].
Product Specifications
CAS Number
1415247-17-4
UNSPSC
12352005
Target
Sigma Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kscm-1.html
Smiles
O=C(N(CCCN1CCCCC1)C2=CC=CC=C2)C3=C(C4=CC(OC)=C(C=C4O3)OC)C
Molecular Formula
C26H32N2O4
Molecular Weight
436.54
References & Citations
[1]Karla-Sue C Marriott, et al. Synthesis of N-phenyl-N- (3- (piperidin-1-yl) propyl) benzofuran-2-carboxamides as new selective ligands for sigma receptors. Bioorg Med Chem. 2012 Dec 1;20 (23) :6856-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Sigma 1 Receptor; Sigma 2 Receptor
Frequently Asked Questions
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