KSCM-1

KSCM-1 is a selective sigma-1 receptor ligand with a Ki of 27.5 nM. KSCM-1 shows more selective for sigma-1 over sigma-2, and shows no significant affinity at non-sigma receptors[1].

Product Specifications

CAS Number

[1415247-17-4]

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/kscm-1.html

Smiles

O=C(N(CCCN1CCCCC1)C2=CC=CC=C2)C3=C(C4=CC(OC)=C(C=C4O3)OC)C

Molecular Formula

C26H32N2O4

Molecular Weight

436.54

References & Citations

[1]Karla-Sue C Marriott, et al. Synthesis of N-phenyl-N- (3- (piperidin-1-yl) propyl) benzofuran-2-carboxamides as new selective ligands for sigma receptors. Bioorg Med Chem. 2012 Dec 1;20 (23) :6856-61.