L-selectin-Fc Chimera, Human, Purified Recombinant Protein
Product Specifications
Background
L-selection (CD26L) is a cell surface adhesion protein constitutively expressed on all classes of human leukocytes. The L-Selectin glycoprotein is composed of a C-type lectin family domain at the amino terminus, an EGF-like domain, two short consensus repeat (SCR) sequences, a transmembrane domain and a short cytoplasmic tail. L-Selectin contains 7 potential N- linked glycosylation sites.
Short Description
L-selectin-Fc Chimera, purified human recombinant protein, suitable to block.
Synonyms
Lymph node homing receptor; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; TQ1; gp90-MEL; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; CD62L; SELL; LNHR; LYAM1
UniProt
P14151
Target
L-selectin
Sequence
A DNA sequence encoding the signal peptide, pro-peptide and extracellular domain of human L-Selectin (amino acids 1-343) was fused to the Fc region of human IgG1 (amino acids 93-330) . The chimeric protein was expressed in modified human 293 cells.
Applications
Block
Format
Purified. The L-Selectin-Fc chimera consists of 20-45% carbohydrate by weight.
Buffer
When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
Precautions
For research use only.
Shipping Conditions
25°C (ambient)
Storage Conditions
Reconstitute with sterile-filtered phosphate-buffered saline to a concentration of 100 μg/mL. Lyophilized products should be stored at 2 to 8°C. Following reconstitution, short-term storage at 2-8°C is recommended and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
Notes
>95% purity, as determined by SDS-PAGE and visualized by silver stain
Host or Source
HEK293
Physical Properties
Lyophilized
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040352-100 1x 100 µL
CD31 / PECAM-1 (158-2B3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940031-100 1x 100 µL
Mucin 5AC (MUC5AC) (45M1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC140017-500 1x 500 µL
Ep-CAM / CD326 (VU-1D9), CF514 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740723-100 1x 100 µL
P53 (BP53-12 + DO-7), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details