Stem cell factor, Human, Purified Recombinant Protein

Product Specifications

Background

Stem Cell Factor (SCF) is a hematopoietic growth factor that stimulates the proliferation of mast cells. SCF also mediates cell-cell adhesion and acts synergistically with other cytokines. The actions of SCF are exerted by binding to the SCF Receptor (PE-1243-50) which results in receptor dimerization. SCF is a type I membrane glycoprotein with 5 potential N-linked glycosylation sites. Soluble SCF is produced by proteolytic cleavage of the extracellular domain.

Short Description

Stem cell factor, purified human recombinant protein, suitable for cell culture.

Synonyms

Kit ligand; C-kit ligand; Stem cell factor; SCF; Mast cell growth factor; MGF; KITLG; MGF; SCF

UniProt

P21583

Target

Stem cell factor

Sequence

A DNA sequence encoding the signal peptide and the mature Stem Cell Factor (SCF) protein of human SCF was expressed in modified human 293 cells.

Applications

Cell Culture

Format

Purified SCF consists of 0-50% carbohydrate by weight.

Buffer

When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Reconstitute with sterile-filtered phosphate-buffered saline to a concentration of 20 μg/mL. Lyophilized products should be stored at 2-8°C. Following reconstitution, short-term storage at 2-8°C is recommended and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.