Anti-Tyrosine Hydroxylase (TH) Antibody

Our Anti-Tyrosine Hydroxylase (TH) ; Tyrosine 3-monooxyegnase rabbit polyclonal primary antibody detects human, mouse, and rat Tyrosine Hydroxylase (TH) ; Tyrosine 3-monooxyegnase, and is affinity-purified. It is validated for use in ICC, IHC-Frozen, WB.

Product Specifications

Background

Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa. In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity (By similarity) . Positively regulates the regression of retinal hyaloid vessels during postnatal development (By similarity) . (Ref: uniprot.org)

Short Description

Synonyms

TH; T-H; tyrosine 3-monooxygenase; monooxygenase; oxidoreductase

UniProt

P07101

Reactivity

Human, Mouse, and Rat

Immunogen

The antibody has been made against the full length recombinant human TH (524 amino acid sequence) expressed in and purified from E. Coli

Target

Tyrosine Hydroxylase (TH) ; Tyrosine 3-monooxyegnase

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ICC, IHC-Frozen, WB

Format

Affinity-purified

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. Store at 4°C for up to one month for short term storage and frequent use.