Anti-Catenin beta Antibody

Our Anti-Catenin beta sheep polyclonal primary antibody detects human, mouse, and rat Catenin beta , and is affinity-purified. It is validated for use in ICC, IHC-Frozen, WB.

Product Specifications

Background

Catenin beta is an adherens junction protein and has a role in the regulation of cell adhesion and in signal transduction through the Wnt pathway. At least 2 isoforms are produced by alternative splicing.

Short Description

Our Anti-Catenin beta sheep polyclonal primary antibody detects human, mouse, and rat Catenin beta, and is affinity-purified. It is validated for use in ICC, IHC-Frozen, WB.

Synonyms

Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; _-Catenin

UniProt

P35222

Reactivity

Human, Mouse, and Rat

Immunogen

A synthetic peptide (C-QSYLDSGIHSGATTTAPSL) corresponding to the amino acid region 28-46 of human Catenin beta coupled to carrier protein KLH. This antibody was designed to detect the active form of Catenin beta . The antibody exhibits a strong preference for dephosphorylated beta catenin protein by western blot but the antibody may show cross reactivity with phosphorylated catenin beta under certain conditions.

Target

Catenin beta

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ICC, IHC-Frozen, WB

Format

Affinity-purified

Buffer

Lyophilized from 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, and 0.05 % sodium azide.

Molecular Weight

86-92 kDa

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. At least 12 months after purchase at 2-8°C (lyophilized formulations) . After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.