Anti-Neurotrophin-4/5 (NT-4/5) Antibody

Our Anti-Neurotrophin-4/5 (NT-4/5) sheep polyclonal primary antibody detects human, mouse, non-human primate, and rat Neurotrophin-4/5 (NT-4/5), and is whole serum. It is validated for use in ELISA, IHC-Frozen, Neutralize, WB.

Product Specifications

Background

FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.

Short Description

Synonyms

Neurotrophin-5; NT-5; Neutrophic factor 5; Neurotrophin-4; NT-4; Neutrophic factor 4; NTF5; NTF4

UniProt

P34130

Reactivity

Human, Mouse, Non-Human Primate, and Rat

Immunogen

Recombinant human NT4

Target

Neurotrophin-4/5 (NT-4/5)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, IHC-Frozen, Neutralize, WB

Format

Whole serum

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for an additional stability.

IHC Dilution

1:500-1:2000

WB Dilution

1:500-1:2000

Specificity

Less than 1% cross-reactivity against NGF, recombinant human BDNF and 5% to NT3 has been shown by 1-site ELISA. Known to react with NT4 from rat and human, mouse and monkey.