Anti-Methyl-CpG- binding protein 2 (MeCP2) Antibody
Our Anti-Methyl-CpG- binding protein 2 (MeCP2) rabbit polyclonal primary antibody detects human, mouse, and rat Methyl-CpG- binding protein 2 (MeCP2), and is affinity purified. It is validated for use in IHC-Frozen, WB.
Product Specifications
Background
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) -containing DNA, with a preference for 5-methylcytosine (5mC) . Ref: uniprot.org
Short Description
Our Anti-Methyl-CpG- binding protein 2 (MeCP2) rabbit polyclonal primary antibody detects human, mouse, and rat Methyl-CpG- binding protein 2 (MeCP2), and is affinity purified. It is validated for use in IHC-Frozen, WB.
Synonyms
CNPase
UniProt
P51608
Reactivity
Human, Mouse, and Rat
Immunogen
A synthetic peptide (REEPVDSRTPVTERVS, aa: 471-486) of C-terminus of human protein.
Target
Methyl-CpG- binding protein 2 (MeCP2)
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC-Frozen, WB
Format
Affinity purified
Buffer
Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide
Precautions
For research use only.
Shipping Conditions
25°C (ambient)
Storage Conditions
Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
IHC Dilution
0.7361111111111112
WB Dilution
1:1000-1:5000
Specificity
Reacts with human, mouse, rat.
Host or Source
Rabbit
Physical Properties
Lyophilized
Isotype
IgG
Immunogen Species
Human
Frequently Asked Questions
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