Anti-Methyl-CpG- binding protein 2 (MeCP2) Antibody

Our Anti-Methyl-CpG- binding protein 2 (MeCP2) rabbit polyclonal primary antibody detects human, mouse, and rat Methyl-CpG- binding protein 2 (MeCP2), and is affinity purified. It is validated for use in IHC-Frozen, WB.

Product Specifications

Background

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) -containing DNA, with a preference for 5-methylcytosine (5mC) . Ref: uniprot.org

Short Description

Synonyms

CNPase

UniProt

P51608

Reactivity

Human, Mouse, and Rat

Immunogen

A synthetic peptide (REEPVDSRTPVTERVS, aa: 471-486) of C-terminus of human protein.

Target

Methyl-CpG- binding protein 2 (MeCP2)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC-Frozen, WB

Format

Affinity purified

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.