Anti-MANF Antibody
Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) rabbit polyclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is affinity-purified. It is validated for use in WB.
Product Specifications
Background
MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson's disease (Lindholm et al., 2008, Voutilainen et al., 2009) . When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Short Description
Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) rabbit polyclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is affinity-purified. It is validated for use in WB.
Synonyms
ARMET, ARP
UniProt
P55145
Reactivity
Human
Immunogen
Recombinant human MANF protein produced using CHO-based cell line. Immunogen is purified from cell culture supernatant.
Target
Mesencephalic astrocyte-derived neurotrophic factor (MANF)
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Format
Affinity-purified
Buffer
Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives.
Precautions
For research use only.
Shipping Conditions
2-8°C (on cold packs)
WB Dilution
1:2000-1:6000
Specificity
MANF (Mesencephalic astrocyte-derived neurotrophic factor) . No cross-reactivity in MANF-knockout mouse. No cross-reactivity with CDNF in IHC, slightly cross-reacts with purified CDNF in WB. No cross-reactivity with CDNF in IHC, slightly cross-reacts with purified CDNF in WB.
Host or Source
Rabbit
Physical Properties
Liquid
Isotype
IgG
Immunogen Species
Human
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040394-500 1x 500 µL
Cytokeratin 19 (Ks19.1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472505-100 1x 100 µL
CD73 (Immuno-Oncology Target) (NT5E/2505), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
LY424842 100 µg
Myeloperoxidase (MPO) (NM_000250) Human Over-expression Lysate
Sign In for Pricing
View Details