Anti-Autophagy-related protein 16-1 (ATG16 L1) Antibody

Our Anti-Autophagy-related protein 16-1 (ATG16 L1) rabbit polyclonal primary antibody detects human and rat Autophagy-related protein 16-1 (ATG16 L1), and is whole serum. It is validated for use in ELISA, ICC, WB.

Product Specifications

Background

ATG16 L1 plays an essential role in autophagy. It is a homooligomer ant interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa) . APG16 L1 localises to the cytoplasm, in particularly to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. There are 5 named isoforms produced by alternative splicing. Genetic variation within ATG16 L1 are associated with susceptibility to inflammatory bowel disease type 1.

Short Description

Synonyms

Autophagy-related protein 16-1; APG16-like 1; ATG16L1

UniProt

Q676U5

Reactivity

Human and Rat

Immunogen

N-terminal of human ATG16-L1 protein conjugated to Blue Carrier Protein has been used as the immunogen.

Target

Autophagy-related protein 16-1 (ATG16 L1)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, ICC, WB

Format

Whole serum

Molecular Weight

22 kDa

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.