Anti-GABARAPL2 Antibody

FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. SUBUNIT: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin. Interacts with ULK1. SUBCELLULAR LOCATION: Golgi apparatus. TISSUE SPECIFICITY: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. SIMILARITY: Belongs to the MAP1 LC3 family. ESTIMATED MOLECULAR WEIGHT: 13.667 kDa.

Our Anti-Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) rabbit polyclonal primary antibody detects human and rat Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2), and is whole serum. It is validated for use in IHC-Frozen, WB.

Gamma-aminobutyric acid receptor-associated protein-like 2; GABA (A) receptor-associated protein-like 2; Ganglioside expression factor 2; GEF-2; General protein transport factor p16; MAP1 light chain 3-related protein; GABARAPL2; FLC3A; GEF2

A synthetic peptide (CVESAKIRAKYP) corresponding to the N-terminal of human GABARAP L2 (GABARAPL2) protein has been used as the immunogen. The sequence is homologous with mouse and rat form of GABARAP L2 (GABARAPL2) .

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

IHC, WB and ELISA confirmed the specificity for GABARAP L2 (GABARAPL2) . A 14 kDa band, that corresponds to the molecular weight of GABARAPL2, is detected via Western blot analysis. Human, rat. Other species not yet tested.