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Anti-Beclin-1 Antibody

Our Anti-Beclin-1 rabbit polyclonal primary antibody detects human Beclin-1 , and is whole serum. It is validated for use in IHC-Frozen.

Product Specifications

Background

Beclin-1 plays a central role in autophagy. It may also play a role in antiviral host defense. It is ubiquitously expressed and it localises to the cytoplasm, golgi apparatus membrane, and in dendrites and cell bodies of cerbellar Purkinje cells. The unprocessed precursor has a length of 450 amino acids and an estimated molecular weight of 51.89 kDa.

Short Description

Our Anti-Beclin-1 rabbit polyclonal primary antibody detects human Beclin-1, and is whole serum. It is validated for use in IHC-Frozen.

Synonyms

Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; APG 6; BECN1

UniProt

Q14457

Reactivity

Human

Immunogen

C-terminal of human Beclin-1 conjugated to Blue Carrier Protein.

Target

Beclin-1

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC-Frozen

Format

Whole serum

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.

IHC Dilution

1:100-1:2000

Specificity

Specific for Beclin-1. Human, other species have not yet been tested.

Host or Source

Rabbit

Physical Properties

Lyophilized

Isotype

Mixed

Immunogen Species

Human

Curated Selection

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