Anti-Noxa Antibody
Our Anti-Noxa rabbit polyclonal primary antibody detects mouse Noxa , and is whole serum. It is validated for use in WB.
Product Specifications
Background
The Bcl-2 family of proteins which regulate apoptosis share identical sequences called Bcl-2 Homology domains (BH1-4) . The BH3 proteins, including BID, NOXA, PUMA, BIK, BIM and BAD are all pro-apoptotic and share sequence identity within the amphipathic alpha-helical BH3 region, which is essential for their apoptotic function. NOXA is highly expressed in adult T-cell leukemia cell line.
Short Description
Our Anti-Noxa rabbit polyclonal primary antibody detects mouse Noxa, and is whole serum. It is validated for use in WB.
Synonyms
PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1; adult T cell leukemia-derived PMA-responsive; Immediate-early-response protein APR; PMA-induced protein 1; Pmaip1; Noxa
UniProt
Q9JM54
Reactivity
Mouse
Immunogen
A synthetic peptide (MPGRKARRNA PVNPTR) as part of mouse Noxa (aa: 1-16) conjugated to diphtheria toxoid
Target
Noxa
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Format
Whole serum
Precautions
For research use only.
Shipping Conditions
25°C (ambient)
Storage Conditions
Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
WB Dilution
1:1000-1:2000
Specificity
Western blot analysis of cells infected with Noxa adenoviruses and BAF indicates a high level of specificity for this antiserum. This antiserum cross-reacts with mouse. Not yet tested in other species.
Host or Source
Rabbit
Physical Properties
Lyophilized
Isotype
Mixed
Immunogen Species
Mouse
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