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Anti-Tyrosine Kinase Receptor C (TrkC) Antibody

Our Anti-Tyrosine Kinase Receptor C (TrkC) mouse monoclonal primary antibody detects human, mouse, and rat Tyrosine Kinase Receptor C (TrkC), and is igg. It is validated for use in FC, ICC.

Product Specifications

Background

Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (Ref: uniprot.org) .

Short Description

Our Anti-Tyrosine Kinase Receptor C (TrkC) mouse monoclonal primary antibody detects human, mouse, and rat Tyrosine Kinase Receptor C (TrkC), and is IgG. It is validated for use in FC, ICC.

Synonyms

GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase

UniProt

Q16288

Reactivity

Human, Mouse, and Rat

Immunogen

Synthetic peptide immunogen, KEPFPESTDNFI, cooresponding to amino acids 397-408 of human TrkC ECD.

Target

Tyrosine Kinase Receptor C (TrkC)

Clonality

Monoclonal

Clone

BS337

Conjugation

Unconjugated

Applications

FC, ICC

Format

IgG

Buffer

Lyophilized from PBS, pH 7.2-7.6 with 0.1% trehalose and contains no preservatives.

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 uL sterile-filtered, ultrapure water to obtain an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) . Avoid repetitive freeze/thaw cycles.

Notes

Protein G purified immunoglobulin from tissue culture supernatants.

Specificity

Human TrkC ECD, cross reactivity to rodent species is expected.

ICC Dilution

1-2 μg/mL

Host or Source

Mouse

Physical Properties

Lyophilized

Isotype

IgG2b, kappa

Immunogen Species

Human

Frequently Asked Questions

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