Anti-S-arrestin (S-AG) Antibody

Our Anti-S-arrestin (S-AG) mouse monoclonal primary antibody detects bovine and pig S-arrestin (S-AG), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Product Specifications

Background

Binds to photoactivated, phosphorylated RHO and terminates RHO signaling via G-proteins by competing with G-proteins for the same binding site on RHO (PubMed: 8003967, PubMed: 25205354) . May play a role in preventing light-dependent degeneration of retinal photoreceptor cells (By similarity) . Ref: uniprot.org

Short Description

Our Anti-S-arrestin (S-AG) mouse monoclonal primary antibody detects bovine and pig S-arrestin (S-AG), and is affinity-purified. It is validated for use in IHC-Frozen, WB.

Synonyms

48 kDa protein, Retinal S-antigen, S-AG, Rod photoreceptor arrestin

UniProt

P08168

Reactivity

Bovine and Pig

Immunogen

Recombinant bovine arrestin-1 with the first 20 amino acids of the C-terminus truncated

Target

S-arrestin (S-AG)

Clonality

Monoclonal

Clone

S128

Conjugation

Unconjugated

Applications

IHC-Frozen, WB

Format

Affinity-purified

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide.

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.

Notes

Protein G purified

IHC Dilution

0.7361111111111112

WB Dilution

3.513888888888889

Specificity

Bovine, reacts with pig. Other species not yet tested. Antibody detects arrestin-1 protein only and does not cross-react with the other 3 arrestin molecules.