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Anti-Pro-glial cell line-derived neurotrophic factor (proGDNF) Antibody

Our Anti-Pro-glial cell line-derived neurotrophic factor (proGDNF) mouse monoclonal primary antibody detects human, mouse (predicted), and rat Pro-glial cell line-derived neurotrophic factor (proGDNF), and is igg. It is validated for use in FC, ICC.

Product Specifications

Background

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake (Ref: uniprot.org) . ProGDNF is the unprocessed precursor molecule of mature GDNF and exists as homodimer.

Short Description

Our Anti-Pro-glial cell line-derived neurotrophic factor (proGDNF) mouse monoclonal primary antibody detects human, mouse (predicted), and rat Pro-glial cell line-derived neurotrophic factor (proGDNF), and is IgG. It is validated for use in FC, ICC.

Synonyms

Glial cell line-derived neurotrophic factor; Astrocyte-derived trophic factor 1; ATF-1

UniProt

P39905

Reactivity

Human, Mouse (Predicted), and Rat

Immunogen

A synthetic peptide (C-EDYPDQFDDVMD, aa: 55-66) of human proGDNF protein has been used as the immunogen. The sequence is located on the pro-domain of the proGDNF full-length protein and is homologous with mouse and rat form of proGDNF.

Target

Pro-glial cell line-derived neurotrophic factor (proGDNF)

Clonality

Monoclonal

Clone

BS376

Conjugation

Unconjugated

Applications

FC, ICC

Format

IgG

Buffer

Lyophilized from a solution containing PBS buffer pH 7.4 with 3% trehalose, without preservatives.

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute in 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Final buffer contains no preservatives.After reconstitution divide into aliquots and store at -20°C for a higher stability. Antibody contains no preservatives. Store at 2-8°C with an appropriate antibacterial agent. Use sterile methods. Highest purity Glycerol (1:1) may be added for an additional stability when stored at refrigerated or freezing temperatures. Avoid repetitive freeze/thaw cycles.

Notes

Protein G purified mouse IgG

Specificity

Human rat. Antibody is expected to detect mouse proGDNF protein due to 100% amino acid sequence homology.

ICC Dilution

1-2 μg/mL

Host or Source

Mouse

Physical Properties

Lyophilized

Isotype

IgG3, kappa

Immunogen Species

Human

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