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Anti-Cerebral dopamine neurotrophic factor (CDNF) Antibody

Our Anti-Cerebral dopamine neurotrophic factor (CDNF) mouse monoclonal primary antibody detects human Cerebral dopamine neurotrophic factor (CDNF), and is igg. It is validated for use in WB.

Product Specifications

Background

DNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

Short Description

Our Anti-Cerebral dopamine neurotrophic factor (CDNF) mouse monoclonal primary antibody detects human Cerebral dopamine neurotrophic factor (CDNF), and is IgG. It is validated for use in WB.

Synonyms

ARMETL1

UniProt

Q49AH0

Reactivity

Human

Immunogen

Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.

Target

Cerebral dopamine neurotrophic factor (CDNF)

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

WB

Format

IgG

Buffer

PBS pH 7.4, with 0.1% sodium azide

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.

Notes

Purified by protein G affinity chromatography

WB Dilution

1:2000-1:4000

Specificity

CDNF (conserved dopamine neurotrophic factor) .

Host or Source

Mouse

Physical Properties

Liquid

Isotype

IgG1

Immunogen Species

Human

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