Anti-Cerebral dopamine neurotrophic factor (CDNF) Antibody
Our Anti-Cerebral dopamine neurotrophic factor (CDNF) mouse monoclonal primary antibody detects human Cerebral dopamine neurotrophic factor (CDNF), and is igg. It is validated for use in WB.
Product Specifications
Background
DNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Short Description
Our Anti-Cerebral dopamine neurotrophic factor (CDNF) mouse monoclonal primary antibody detects human Cerebral dopamine neurotrophic factor (CDNF), and is IgG. It is validated for use in WB.
Synonyms
ARMETL1
UniProt
Q49AH0
Reactivity
Human
Immunogen
Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.
Target
Cerebral dopamine neurotrophic factor (CDNF)
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Format
IgG
Buffer
PBS pH 7.4, with 0.1% sodium azide
Precautions
For research use only.
Shipping Conditions
25°C (ambient)
Storage Conditions
Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.
Notes
Purified by protein G affinity chromatography
WB Dilution
1:2000-1:4000
Specificity
CDNF (conserved dopamine neurotrophic factor) .
Host or Source
Mouse
Physical Properties
Liquid
Isotype
IgG1
Immunogen Species
Human
Curated Selection
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