Anti-MANF Antibody
Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) mouse monoclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is igg. It is validated for use in WB.
Product Specifications
Background
MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson's disease (Lindholm et al., 2008, Voutilainen et al., 2009) . When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Short Description
Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) mouse monoclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is IgG. It is validated for use in WB.
Synonyms
ARMET, ARP
UniProt
P55145
Reactivity
Human
Immunogen
Recombinant human MANF protein produced using CHO-based cell line. Immunogen is purified from cell culture supernatant.
Target
Mesencephalic astrocyte-derived neurotrophic factor (MANF)
Clonality
Monoclonal
Conjugation
Unconjugated
Applications
WB
Format
IgG
Buffer
PBS pH 7.4, with 0.1% sodium azide
Precautions
For research use only.
Shipping Conditions
25°C (ambient)
Storage Conditions
Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.
Notes
Purified with Protein G affinity chromatography
IHC Dilution
1-10 μg/mL
WB Dilution
0.5-2 μg/mL
Specificity
MANF (Mesencephalic astrocyte-derived neurotrophic factor) .
ICC Dilution
1-10 μg/mL
Host or Source
Mouse
Physical Properties
Liquid
Isotype
IgG1
Immunogen Species
Human
Curated Selection
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