Anti-MANF Antibody

Our Anti-Mesencephalic astrocyte-derived neurotrophic factor (MANF) mouse monoclonal primary antibody detects human Mesencephalic astrocyte-derived neurotrophic factor (MANF), and is igg. It is validated for use in WB.

Product Specifications

Background

MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson's disease (Lindholm et al., 2008, Voutilainen et al., 2009) . When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

Short Description

Synonyms

ARMET, ARP

UniProt

P55145

Reactivity

Human

Immunogen

Recombinant human MANF protein produced using CHO-based cell line. Immunogen is purified from cell culture supernatant.

Target

Mesencephalic astrocyte-derived neurotrophic factor (MANF)

Clonality

Monoclonal

Conjugation

Unconjugated

Applications

Format

IgG

Buffer

PBS pH 7.4, with 0.1% sodium azide

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.