Anti-Spectrin alpha chain, non-erythrocytic 1 Antibody

Our Anti-Spectrin alpha chain, non-erythrocytic 1 mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Spectrin alpha chain, non-erythrocytic 1 , and is affinity-purified. It is validated for use in FC, ICC, IHC-Frozen, WB.

Product Specifications

Background

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. The Spectrins form into dimers and further into tetramers of alpha and beta subunits (Ref: Entrez Gene) . The alpha-II subunit is widely expressed in tissues but, in the nervous system, is found predominantly in neurons.

Short Description

Our Anti-Spectrin alpha chain, non-erythrocytic 1 mouse monoclonal primary antibody detects bovine, human, mouse, pig, and rat Spectrin alpha chain, non-erythrocytic 1, and is affinity-purified. It is validated for use in FC, ICC, IHC-Frozen, WB.

Synonyms

SPTAN1; alpha II spectrin; alpha Fodrin; Spectrin, non-erythroid alpha chain; SPTA2

UniProt

Q13813

Reactivity

Bovine, Human, Mouse, Pig, and Rat

Immunogen

This antibody was raised against a recombinant construct containing the seventh, eight and ninth repeats (amino acids 676-1043) of human alpha-II Spectrin. The 9th spectrin repeat also includes a Src-homology 3 domain. This construct was expressed in and purified from E. coli.

Target

Spectrin alpha chain, non-erythrocytic 1

Clonality

Monoclonal

Clone

3D7

Conjugation

Unconjugated

Applications

FC, ICC, IHC-Frozen, WB

Format

Affinity-purified

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

Molecular Weight

240 kDa

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. Aliquot and store at -20°C for a higher stability and at 2-8°C with an appropriate antibacterial agent. Avoid freeze-thaw cycles.