Anti-TAR DNA-binding protein 43 (TDP-43) Antibody

Our Anti-TAR DNA-binding protein 43 (TDP-43) mouse monoclonal primary antibody detects human, mouse, other mammals (predicted), and rat TAR DNA-binding protein 43 (TDP-43), and is igg. It is validated for use in ICC, IHC-Frozen, WB.

Product Specifications

Background

TAR DNA-binding protein 43 (TDP43) is a DNA and RNA-binding protein which regulates transcription and splicing (ref: SWISSPROT) .

Short Description

Our Anti-TAR DNA-binding protein 43 (TDP-43) mouse monoclonal primary antibody detects human, mouse, other mammals (predicted), and rat TAR DNA-binding protein 43 (TDP-43), and is IgG. It is validated for use in ICC, IHC-Frozen, WB.

Synonyms

TAR DNA-binding protein 43; TDP-43; TARDBP; TDP43

UniProt

Q13148

Reactivity

Human, Mouse, Other Mammals (Predicted), and Rat

Immunogen

This antibody was raised against recombinant full length human his-tagged TDP43 which was expressed in E. coli and purified by nickel affinity.

Target

TAR DNA-binding protein 43 (TDP-43)

Clonality

Monoclonal

Clone

3H8

Conjugation

Unconjugated

Applications

ICC, IHC-Frozen, WB

Format

IgG

Buffer

Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, and sodium azide

Molecular Weight

43 kDa

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water to achieve a 1 mg/mL concentration. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.

Notes

Protein G purified

IHC Dilution

1:1000-1:5000

WB Dilution

1:1000-1:5000

Specificity

The specificity of this antibody has been confirmed by WB. This antibody detects ~43 kDa TDP43 protein on crude extract of mouse brain nuclear fraction. Human and Rodent. Predicted to react with other mammalian tissue.