Anti-GDNF family receptor alpha-4 (GFR alpha-4) Antibody
Our Anti-GDNF family receptor alpha-4 (GFR alpha-4) chicken polyclonal primary antibody detects human GDNF family receptor alpha-4 (GFR alpha-4), and is affinity-purified. It is validated for use in IHC-Frozen, WB.
Product Specifications
Background
GFRa-4 belongs to the GDNF receptor family. It is a glycosyl-phosphatidylinositol (GPI) -linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor.
Short Description
Our Anti-GDNF family receptor alpha-4 (GFR alpha-4) chicken polyclonal primary antibody detects human GDNF family receptor alpha-4 (GFR alpha-4), and is affinity-purified. It is validated for use in IHC-Frozen, WB.
Synonyms
GDNF receptor alpha-4; Persephin receptor; GDNFR-alpha-4; GFR-alpha-4
UniProt
Q9GZZ7
Reactivity
Human
Immunogen
Recombinant His-tagged human GFRa-4 protein produced using CHO-based cell line. For production of hGFRa-4, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
Target
GDNF family receptor alpha-4 (GFR alpha-4)
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC-Frozen, WB
Format
Affinity-purified
Buffer
Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives.
Precautions
For research use only.
Shipping Conditions
2-8°C (on cold packs)
Storage Conditions
Ready to dilute once thawedStore at -80°C upon receipt. Divide antibody into aliquots upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
WB Dilution
1:5000-1:10000
Specificity
Human GFRa-4. This antibody does not cross-react with hGFRa-1, hGFRa-2, hGFRa-3.
ICC Dilution
1:1000-1:3000
Host or Source
Chicken
Physical Properties
Liquid
Isotype
IgY
Immunogen Species
Human
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