Anti-GDNF family receptor alpha-3 (GFR alpha-3) Antibody
Our Anti-GDNF family receptor alpha-3 (GFR alpha-3) chicken polyclonal primary antibody detects human GDNF family receptor alpha-3 (GFR alpha-3), and is affinity-purified. It is validated for use in ICC, WB.
Product Specifications
Background
The GFRa-3 is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin.
Short Description
Our Anti-GDNF family receptor alpha-3 (GFR alpha-3) chicken polyclonal primary antibody detects human GDNF family receptor alpha-3 (GFR alpha-3), and is affinity-purified. It is validated for use in ICC, WB.
Synonyms
GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3; GFRA3
UniProt
O60609
Reactivity
Human
Immunogen
Recombinant His-tagged human GFRa-3 protein produced using CHO-based cell line. For production of hGFRa-3, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
Target
GDNF family receptor alpha-3 (GFR alpha-3)
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
ICC, WB
Format
Affinity-purified
Buffer
Concentrated ammonium sulphate in PBS pH 7.4 containing no preservatives.
Precautions
For research use only.
Shipping Conditions
2-8°C (on cold packs)
WB Dilution
1:5000-1:10000
Specificity
Human GFRa-3. No cross-reactivity with hGFRa-1, hGFRa-2, hGFRa-4.
ICC Dilution
1:1500-1:3000
Host or Source
Chicken
Physical Properties
Liquid
Isotype
IgY
Immunogen Species
Human
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