Anti-Presenilin-1 (PS-1) Antibody

Our Anti-Presenilin-1 (PS-1) chicken polyclonal primary antibody detects human, mouse, and rat Presenilin-1 (PS-1), and is affinity-purified. It is validated for use in ELISA, WB.

Product Specifications

Background

Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot) .

Short Description

Our Anti-Presenilin-1 (PS-1) chicken polyclonal primary antibody detects human, mouse, and rat Presenilin-1 (PS-1), and is affinity-purified. It is validated for use in ELISA, WB.

Synonyms

Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1

UniProt

P49768

Reactivity

Human, Mouse, and Rat

Immunogen

Mixture of two human Presenilin 1 peptides (311-322 and 341-352 aa) . Both sequences are highly conserved in human, mouse and rat.

Target

Presenilin-1 (PS-1)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ELISA, WB

Format

Affinity-purified

Buffer

PBS with 0.02% sodium azide.

Precautions

For research use only.

Shipping Conditions

2-8°C (on cold packs)

Storage Conditions

Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

WB Dilution

1:1000-1:4000

Specificity

Human Presenilin 1.

Host or Source

Chicken

Physical Properties

Liquid

Isotype

IgY

Immunogen Species

Human

Curated Selection

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