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Anti-Casein kinase I isoform alpha (CKI-alpha) Antibody

Our Anti-Casein kinase I isoform alpha (CKI-alpha) chicken polyclonal primary antibody detects bovine, chicken, horse, human, mouse, pig, and rat Casein kinase I isoform alpha (CKI-alpha), and is igy preparation. It is validated for use in ICC, IHC-Frozen, WB.

Product Specifications

Background

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. (Reference: uniprot.org)

Short Description

Our Anti-Casein kinase I isoform alpha (CKI-alpha) chicken polyclonal primary antibody detects bovine, chicken, horse, human, mouse, pig, and rat Casein kinase I isoform alpha (CKI-alpha), and is IgY preparation. It is validated for use in ICC, IHC-Frozen, WB.

Synonyms

CK1; CKI-alpha

UniProt

P48729

Reactivity

Bovine, Chicken, Horse, Human, Mouse, Pig, and Rat

Immunogen

Shortest isoform of recombinant full length CK1a.

Target

Casein kinase I isoform alpha (CKI-alpha)

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

ICC, IHC-Frozen, WB

Format

IgY preparation

Buffer

Lyophilized IgY preparation, with sodium azide.

Molecular Weight

38 kDa

Precautions

For research use only.

Shipping Conditions

25°C (ambient)

Storage Conditions

Spin vial briefly before opening. Reconstitute with 100 μL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.

WB Dilution

1:5000-1:10000

Specificity

Antibody recognizes CK1 by Western blot and immunohistochemistry. Cross reactivity.

ICC Dilution

1:500-1:1000

Host or Source

Chicken

Physical Properties

Lyophilized

Isotype

IgY

Immunogen Species

Human

Curated Selection

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