CAR Modulation Antibody Panel

Product Specifications

Background

This antibody panel consists of the following: ICH5024-0.1mg Muromonab Biosimilar ICH5023-0.1mg Theralizumab Biosimilar ICH5015-0.1mg Urelumab Biosimilar ICH4029-0.1mg Pembrolizumab Biosimilar ICH4018-0.1mg Atezolizumab Biosimilar ICH5077-0.1mg Fresolimumab Biosimilar

Reactivity

Human

Target

CD3, CD28, 4-1BB, PD-1, PD-L1, TGF-B

Applications

Functional Assays

Purification Method

All the monoclonal antibodies in this panel were purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

>1.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.

Fragment

IgG2a CH1+Human IgG1 CH2+CH3-Kappa (muromonab), Human IgG4 (theralizumab), Human IgG1 (urelumab), Human IgG4 kappa (pembrolizumab), Human IgG1 Kappa (atezolizumab), Human IgG4 S228P Kappa (fresolimumab)