Mouse Immune CheckPoint Antibody Panel
Product Specifications
Background
This antibody panel consists of the following: ICH1132 anti-mouse PD-1 antibody (RMP1-14) ICH1086 anti-mouse PD-L1 antibody (10F.9G2) ICH1096 anti-mouse CTLA-4 antibody (9D9) ICH1078 anti-mouse LAG-3 antibody (C9B7W) ICH1220 anti-mouse TIGIT antibody (1G9) ICH1036 anti-mouse 4-1BB antibody (3H3) ICH1133 anti-mouse TIM-3 antibody (RMT3-23) if selected ICH1261 anti-mouse GITR antibody (DTA-1) if selected
Host
Mouse,Rat
Reactivity
Mouse
Target
PD-1, PD-L1, CTLA-4, TIGIT, LAG-3, 4-1BB as standard, plus TIM-3 and GITR if selected
Clone
RMP1-14, 10F.9G2, 9D9, 1G9, C9B7W, 3H3, plus RMT3-23 and DTA-1 if selected
Applications
Clone Dependent
Purification Method
All the monoclonal antibodies in this panel were purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
>1.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Fragment
Rat IgG2a (RMP1-14), Rat IgG2b (10F.9G2), IgG2b (9D9), Rat IgG1 (C9B7W), IgG1 (1G9) and Rat IgG2a (RMT3-23), IgG2a (DTA-1)
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
These antibodies are for research use only (RUO) : they are not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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