Glembatumumab Vedotin Biosimilar - Research Grade
Product Specifications
Background
Glembatumumab vedotin targets GPNMB, a protein located specifically on the surface of melanoma cells. After Glembatumumab vedotin binds to GPNMB, it is transported inside the cancer cell where the chemotherapy payload, Auristatin E, is cleaved from the antibody and activated.
Product Name Alternative
MMAE
Host
CHO Cells
Reactivity
Human
Target
GPNMB
Isotype
IgG2
Applications
Functional Assays
Concentration
1mg/mL
Purity
>90% by SDS-PAGE
Shipping Conditions
Room Temp
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Applications Notes
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
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