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Glembatumumab Vedotin Biosimilar - Research Grade

Product Specifications

Background

Glembatumumab vedotin targets GPNMB, a protein located specifically on the surface of melanoma cells. After Glembatumumab vedotin binds to GPNMB, it is transported inside the cancer cell where the chemotherapy payload, Auristatin E, is cleaved from the antibody and activated.

Product Name Alternative

MMAE

Host

CHO Cells

Reactivity

Human

Target

GPNMB

Isotype

IgG2

Applications

Functional Assays

Concentration

1mg/mL

Purity

>90% by SDS-PAGE

Shipping Conditions

Room Temp

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Formulation

25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Applications Notes

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

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