Tremelimumab Biosimilar - Research Grade
Product Specifications
Background
Uses the same sequence as the therapeutic antibody Tremelimumab
Host
CHO Cells
Reactivity
Human
Target
CTLA-4
Isotype
IgG2 κ
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Specificity
Detects human CTLA-4
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
Bulk Human IgG2 Isotype Control (IB2) [ICH2255]
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