Vudalimab Biosimilar - Research Grade
Product Specifications
Background
Uses the same sequence as the therapeutic antibody Vudalimab
Reactivity
Human
Target
PD-1 + CTLA-4
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
>90% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Fragment
Human IgG1 (N208D/E233P/L234V/L235A/G236Del/S267K/Q295E/L368D/K370S/N384D/Q418E/N421D/M428L/N434S) -Kappa
Specificity
Detects human PD-1 and human CTLA-4
Formulation
20mM His/Asp, pH 5.0, Contains no stabilizers or preservatives
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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