Teplizumab Biosimilar - Research Grade
Product Specifications
Background
Uses the same sequence as the therapeutic antibody Teplizumab
Product Name Alternative
CD3E, IMD18, T3E, TCRE, CD3e molecule, CD3epsilon, CD3 epsilon subunit of T-cell receptor complex
Reactivity
Human
Target
CD3E
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Fragment
Human IgG1 (L234A/L235A/E356D/M358L) -Kappa
Specificity
Detects human CD3E
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
ICH2254LALA
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