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Teplizumab Biosimilar - Research Grade

Product Specifications

Background

Uses the same sequence as the therapeutic antibody Teplizumab

Product Name Alternative

CD3E, IMD18, T3E, TCRE, CD3e molecule, CD3epsilon, CD3 epsilon subunit of T-cell receptor complex

Reactivity

Human

Target

CD3E

Sequence

https://www.imgt.org/mAb-DB/

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

<1EU/mg Determined by LAL gel clotting assay

Purity

≥95% monomer by analytical SEC, >95% by SDS Page

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Fragment

Human IgG1 (L234A/L235A/E356D/M358L) -Kappa

Specificity

Detects human CD3E

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

ICH2254LALA

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