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Tusamitamab Ravtansine Biosimilar - Research Grade

Product Specifications

Background

Tusamitamab ravtansine is a novel antibody-drug conjugate that selectively targets CEACAM5, a cell surface glycoprotein highly expressed in several tumor types. Tusamitamab ravtansine showed promising antitumor activity in patients (pts) with heavily pretreated NSQ NSCLC and high CEACAM5 expression.

Product Name Alternative

DM4

Host

CHO Cells

Reactivity

Human

Target

CEACAM5 / CEA / CD66e

Isotype

IgG1

Applications

Functional Assays

Concentration

1mg/mL

Purity

>90% by SDS-PAGE

Shipping Conditions

Room Temp

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Formulation

25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)

Applications Notes

Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

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