Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Urelumab Biosimilar - Research Grade

Product Specifications

Background

RUO urelumab is a humanized agonistic monoclonal antibody targeting 4-1BB with potential immunostimulatory and antineoplastic activities. Urelumab specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. .

Product Name Alternative

4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137

UniProt

Q07011

Reactivity

Human

Target

4-1BB

Isotype

IgG1

Sequence

https://www.imgt.org/mAb-DB/

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE

Buffer

ICH3002

References & Citations

Lee et al. A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity. Journal of Experimental & Clinical Cancer Research

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Specificity

Detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Urelumab.

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

KIFC3 Human qPCR Template Standard (NM_005550)
HK204191 1 Kit

KIFC3 Human qPCR Template Standard (NM_005550)

Ask
View Details
IL1RA (IL1RN) Mouse Monoclonal Antibody [Clone ID: OTI5C5]
TA803295 100 µL

IL1RA (IL1RN) Mouse Monoclonal Antibody [Clone ID: OTI5C5]

Ask
View Details
Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)
MBS1212928-01 0.02 mg (E-Coli)

Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)
MBS1212928-02 0.1 mg (E-Coli)

Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)
MBS1212928-03 0.02 mg (Yeast)

Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)

Ask
View Details
Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)
MBS1212928-04 0.1 mg (Yeast)

Recombinant Edwardsiella ictaluri Nucleoside diphosphate kinase (ndk)

Ask
View Details