Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Sutimlimab Biosimilar - Research Grade

Product Specifications

Background

RUO sutimlimab biosimilar is a humanized monoclonal antibody that is designed to selectively target and inhibit C1s in the classical complement pathway, which is part of the innate immune system. By blocking C1s, sutimlimab inhibits the activation of the classical complement pathway with the goal of halting C1-activated hemolysis in cold agglutinin disease to prevent the abnormal destruction of healthy red blood cells. By selectively inhibiting the classical pathway upstream at C1s, sutimlimab does not inhibit the lectin and alternative complement pathways.

Product Name Alternative

EDSPD2, complement C1s

UniProt

P09871

Reactivity

Human

Target

C1s

Isotype

IgG4

Sequence

https://www.imgt.org/mAb-DB/

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Product Datasheet

https://ichor.bio/productpdf/print/index/url_key/sutimlimab-biosimilar-research-grade/

Specificity

Detects human C1s. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sutimlimab.

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LRFN1 Antibody
24851 100 µL

LRFN1 Antibody

Ask
View Details
MRPS26 Antibody
E51A11034 100 µL

MRPS26 Antibody

Ask
View Details
RNA Helicase A (DHX9) Human siRNA Oligo Duplex (Locus ID 1660)
SR319909 1 Kit

RNA Helicase A (DHX9) Human siRNA Oligo Duplex (Locus ID 1660)

Ask
View Details
MRC1 Recombinant Antibody, Cy3 Conjugated
bsm-52791R-Cy3-TR 20 µL

MRC1 Recombinant Antibody, Cy3 Conjugated

Ask
View Details