Cetuximab Biosimilar - GAALIE Research Grade
Product Specifications
Background
GAALIE mutations increase the affinity binding of IgG1 to the Fc activating receptors.
Product Name Alternative
Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1
UniProt
P00533
Host
CHO Cells
Reactivity
Human
Target
EGFR
Sequence
https://www.imgt.org/mAb-DB/
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3001-100ml ICH3002-100ml ICH3003-100ml
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Fragment
Human IgG1 (Mutation) -kappa
Specificity
Detects human EGFR.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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